The Ministry of Lost Souls
Systematic Chaos
Length 14:57
Working title Schindler's Lisp
Release date June 4th, 2007
Lyrics John Petrucci
Music Dream Theater
First live performance
Total live plays
Recorded Avatar Studios
Other appearances Chaos in Motion
Previous song Prophets of War
Next song In the Presence of Enemies (Pt. 2)

At 14:57, "The Ministry of Lost Souls" is the album's second longest track. Throughout the song's lyrics, Petrucci tells of a person who dies in the process of saving a woman from drowning. However, the woman who is saved is filled with "regret and sorrow" until she is able to re-unite with her rescuer. The title for the track during recording was, "Schindler's Lisp" and it was the fourth song to be written.

However, there could be another interpretation of the lyrics. It could be about a woman wanting to kill herself, wanting to jump in the water but a man refrains her. But as she continues to suffer, and the man can't convince her anymore to stay alive, he finally "accepts" her to commit suicide ("It's time I release you from this life").